Programme

Anastassis Perrakis; NKI

EM: "The fortuitous discovery of a druggable pocket - and an antiviral drug - in the SARS-CoV-2 spike"

NMR: "Resolving Protein–Ligand Binding Pathways by NMR relaxation: Conformational Selection vs Induced Fit"

Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5 helicase

Radiation damage and metal identification in Structural Biology: why do we care?

Visualizing electrons in redox proteins by single particle cryo-EM

EasyGrid: a versatile platform for automated Cryo-EM sample preparation and control

Advances in the stream processing of single particles by CryoEM

Detecting protein-drug interactions in human cells by real-time 19F NMR

Light-NMR: what can we learn about photo-transformable fluorescent proteins?

Streamlining cryo-corellative multi-scale imaging of multicellular samples

Advancing Correlative Microscopy: Automated Alignment of cryo-3D-SIM and Soft X-ray Tomography Data – Strategies and Implementation

Building a Fragment Screening Data Pilot Repository: Challenges and Opportunities

Controlling the Formation of Functional Amyloids: the Example of GLP-1 Analogues and Related Polypeptide Hormones

Molecular mechanisms of MICAL signaling in cytoskeletal dynamics

A divide-and-conquer structural biology approach to elucidate the photocycle of light-regulated transcription factor EL222

Seeing the light: Integrative structural biology insights into photoreceptor mechanism

Ultrastructural details of the bacterial spore revealed by in situ cryo-electron tomography

Hybrid methods for analyzing conformational variability in cryo-EM and cryo-ET data

Measuring in-cell NMR of nucleic acids, first T1 results

Impact of osteosarcoma cells differentiation on biomineralization and mitochondrial morphology

In situ NMR spectroscopy reveals the structural details of outer membrane protein OmpA within the native membrane

Structural and functional characterisation of mechanisms controlling epithelial tissue integrity.

Characterizing biomolecular structure and interactions in living human cells synchronized in defined physiological states using NMR spectroscopy

Lac Repressor allostery

High-resolution cryo-EM analysis of ribosome and virus complexes

Ribosomes hibernate on mitochondria during cellular stress